Severe weather spawned more than 50 tornadoes as the storms swept the South over the weekend, leaving widespread damage and claiming at least two lives.

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A high-end EF2 tornado struck Greensboro, North Carolina, on Sunday evening, causing damage to homes and buildings. Anthony George, 48, was killed when a tree fell on his vehicle in northern Greensboro on Sunday evening, the Greensboro News and Record reported. The tree injured two other women when also it fell on their vehicles.

Twenty-month-old Carli Ortiz was killed Friday when a tree fell on the RV where she was sleeping in Haughton, Louisiana. The Bossier Parish Sheriff's Office reported that four adults and a 15-month-old were also in the RV, but no other injuries were sustained.

(MORE: The Latest on the Severe Storms That Battered the South)

At least 11 tornadoes were confirmed in Arkansas, two of which were EF2 in strength, causing multiple injuries and damaging an estimated 160 buildings, emergency crews reported on Friday. At least five confirmed tornadoes struck throughout Missouri over the weekend, destroying homes and uprooting trees.

Virginia Gov. Ralph Northam declared a state of emergency after an EF3 tornado hit near Lynchburg, Virginia, on Sunday, according to the National Weather Service. The storm left several buildings damaged in Campbell County, as well as flipped cars and downed trees.

It was only the second EF3-or-stronger tornado to strike the U.S. in 2018 so far.